https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:2868 Wed 24 Jul 2013 22:53:24 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9206 0.9). Agreement for safe maximal lift identification was good. Conclusions: Ratings demonstrated substantial levels of intra-rater and inter-rater reliability for the lifting components of the WorkHab FCEs.]]> Wed 11 Apr 2018 16:02:42 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10468 Wed 11 Apr 2018 13:19:21 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14416 Wed 11 Apr 2018 12:40:59 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9204 Wed 11 Apr 2018 10:55:44 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14595 Wed 04 Sep 2019 11:33:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16899 Tue 23 Jul 2019 12:25:16 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16898 Tue 23 Jul 2019 12:22:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3957 Sat 24 Mar 2018 10:58:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9657 Sat 24 Mar 2018 10:47:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9463 Sat 24 Mar 2018 10:45:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9469 Sat 24 Mar 2018 10:45:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9474 Sat 24 Mar 2018 10:45:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8010 Sat 24 Mar 2018 08:42:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7993 Sat 24 Mar 2018 08:42:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7198 Sat 24 Mar 2018 08:42:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7293 Sat 24 Mar 2018 08:42:13 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7929 Sat 24 Mar 2018 08:41:42 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8292 Sat 24 Mar 2018 08:40:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7531 Sat 24 Mar 2018 08:38:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7091 Sat 24 Mar 2018 08:38:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8332 Sat 24 Mar 2018 08:36:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7342 Sat 24 Mar 2018 08:35:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7333 Sat 24 Mar 2018 08:35:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8035 Sat 24 Mar 2018 08:35:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7148 Sat 24 Mar 2018 08:34:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8274 Sat 24 Mar 2018 08:33:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:990 Sat 24 Mar 2018 08:29:50 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15337 Sat 24 Mar 2018 08:26:44 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14780 Sat 24 Mar 2018 08:26:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14782 Sat 24 Mar 2018 08:26:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14784 120 beats per minute. Two papers specified a minimum episode frequency and four papers required a minimum syndrome duration. Conclusions: Of necessity, diagnostic criteria have been developed ad hoc. The differences between criteria complicate both clinical diagnosis and the process of comparing research cohorts. These findings demarcate the need for a single set of PSH diagnostic criteria and provide the substrate for scientific consensus.]]> Sat 24 Mar 2018 08:26:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14786 Sat 24 Mar 2018 08:26:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14789 Sat 24 Mar 2018 08:26:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14792 Sat 24 Mar 2018 08:26:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14787 Sat 24 Mar 2018 08:26:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14407 Sat 24 Mar 2018 08:24:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14405 1000 U/L) and treatment (single dose-activated charcoal [SDAC] and NAC) were analysed. Data were analysed within a repeated measures logistic regression framework using NONMEM (ver 7.2). The primary outcome was administration of NAC, which was determined based on a serum paracetamol concentration greater than the nomogram line. Result.: There were 1571 admissions in 1303 patients, with a median age of 27 years (12–96 years) and 1140 (73%) were females. The median dose was 10 g (1–100 g). The paracetamol concentration was above the nomogram line in 337 of 1571 (22%) patients. Patients presenting later (first paracetamol concentration between 7 and 16 h post-overdose) compared to those presenting earlier (4–7 h post-overdose) were more likely to have hepatotoxicity (5.5% vs. 0.4%; p < 0.0001), have a toxic paracetamol concentration (34% vs. 18%; p  0.0001) and receive NAC (48% vs. 23%; p < 0.0001). SDAC reduced the probability of the paracetamol concentration being above the nomogram. Based on SDAC not being administered there was a 5% probability of requiring NAC at a dose of 6–9 g, a 10% chance of requiring NAC at a dose of 13–16 g, a 50% chance of requiring NAC at a dose of 30–34 g and a 90% chance for needing NAC at 48–50 g. Conclusion. Reported dose was a good predictor of a toxic paracetamol concentration and SDAC reduced the probability of the concentration being above the nomogram. These predictions may assist in determining which patients could be started on NAC immediately.]]> Sat 24 Mar 2018 08:24:53 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14372 Sat 24 Mar 2018 08:23:10 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14573 Sat 24 Mar 2018 08:22:42 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14580 Sat 24 Mar 2018 08:22:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14577 Sat 24 Mar 2018 08:22:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14578 Sat 24 Mar 2018 08:22:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14583 Sat 24 Mar 2018 08:22:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14882 Sat 24 Mar 2018 08:22:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14497 Sat 24 Mar 2018 08:21:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14494 Sat 24 Mar 2018 08:21:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14446 Sat 24 Mar 2018 08:20:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14585 Sat 24 Mar 2018 08:20:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14611 Sat 24 Mar 2018 08:20:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14610 Sat 24 Mar 2018 08:20:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14589 Sat 24 Mar 2018 08:20:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14586 Sat 24 Mar 2018 08:20:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14552 Sat 24 Mar 2018 08:19:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14457 120 mg) identified from admissions to a toxicology unit between January 1987 and August 2013. Demographic information, details of ingestion, clinical effects, ECG parameters (HR, QT and QRS), and length of stay were extracted from a clinical database. Results: From 267 mirtazapine overdoses, there were 89 single-agent mirtazapine ingestions and 178 cases where mirtazapine was taken with at least one other drug. The median age of the 89 single-agent mirtazapine ingestions was 36 years [interquartile range (IQR): 26 – 49 years; Range: 15 – 81 years]; 45 were female (51%). The median ingested dose was 420 mg (IQR: 270 – 750 mg; Range: 150 – 1350 mg) and 41 patients (46%) had a Glasgow coma score (GCS) < 15, but the minimum GCS was 10. There were no seizures, serotonin toxicity or delirium. Tachycardia occurred in 29 patients (33%) and hypertension in 32 patients (36%). The median QRS was 80 ms (Range: 80 – 120 ms) and there were no cases with QT prolongation. There were no arrhythmias and no deaths. The median length of stay was 14 h (IQR: 8.8 – 18.2 h; Range:2.2 – 75 h). No single-agent mirtazapine patient was admitted to intensive care. The 178 patients taking co-ingestants had more severe toxicity depending on the co-ingested drug. Conclusion: Mirtazapine appears to be relatively benign in overdose, associated with tachycardia, mild hypertension and mild CNS depression not requiring intervention.]]> Sat 24 Mar 2018 08:19:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14460 Sat 24 Mar 2018 08:19:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14454 Sat 24 Mar 2018 08:19:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14549 Sat 24 Mar 2018 08:18:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14538 Sat 24 Mar 2018 08:18:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12776 Sat 24 Mar 2018 08:18:20 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13647 Sat 24 Mar 2018 08:17:07 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13266 Sat 24 Mar 2018 08:16:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13274 Sat 24 Mar 2018 08:15:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12860 Sat 24 Mar 2018 08:14:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10440 106 cfu/mL) was cultured from the sputum of 17 (15%) subjects with stable asthma and was associated with higher total cell counts, proportion and number of neutrophils, sputum IL-8 and 8-isoprostane concentrations. The role of bacteria in potentiating neutrophilic asthma warrants further investigation. Therapies such as antibiotic and antioxidant treatment may be most effective in this sub-group of patients.]]> Sat 24 Mar 2018 08:13:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10439 Sat 24 Mar 2018 08:13:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10261 Sat 24 Mar 2018 08:13:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10464 Sat 24 Mar 2018 08:09:13 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10458 Sat 24 Mar 2018 08:09:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10463 Sat 24 Mar 2018 08:09:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10470 Sat 24 Mar 2018 08:09:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10465 Sat 24 Mar 2018 08:09:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10454 0.05). Median admission plasma-paraquat concentration in patients with peripheral burning (2.67 μg/mL, 95% CI = 0.84–14.2) was significantly higher than in the patients with no peripheral burning (0.022 μg/mL, 95% CI = 0.005–0.78; p < 0.001). Peripheral burning has a sensitivity of 0.72 (95% CI = 0.6–8) and specificity of 0.74 (95% CI = 0.64–0.08) and a positive predictive value of 0.73 (95% CI = 0.6–0.8). Discussion: It is possible that this symptom may help discriminate between patients who have poor chance of survival and those who may potentially benefit from interventions. The mechanism is not clear but could either include a direct concentration-related effect or be a marker of oxidative stress. Conclusion: Presence of burning sensation is associated with high plasma-paraquat concentrations and is strongly predictive of death.]]> Sat 24 Mar 2018 08:08:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20348 Sat 24 Mar 2018 08:02:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19523 Sat 24 Mar 2018 08:02:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16523 Sat 24 Mar 2018 08:01:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16887 Sat 24 Mar 2018 08:00:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16891 Sat 24 Mar 2018 08:00:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16892 Sat 24 Mar 2018 08:00:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16905 Sat 24 Mar 2018 07:59:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16897 Sat 24 Mar 2018 07:58:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16900 Sat 24 Mar 2018 07:58:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16901 Sat 24 Mar 2018 07:58:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19833 Sat 24 Mar 2018 07:57:08 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19371 Sat 24 Mar 2018 07:52:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18771 Sat 24 Mar 2018 07:51:09 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5544 Sat 24 Mar 2018 07:49:13 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5422 Sat 24 Mar 2018 07:48:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4952 Sat 24 Mar 2018 07:48:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5751 Sat 24 Mar 2018 07:45:00 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25447 Sat 24 Mar 2018 07:32:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4718 Sat 24 Mar 2018 07:21:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4777 Sat 24 Mar 2018 07:20:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4823 Sat 24 Mar 2018 07:18:53 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4852 Sat 24 Mar 2018 07:18:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4869 Sat 24 Mar 2018 07:18:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22268 Sat 24 Mar 2018 07:17:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22257 Sat 24 Mar 2018 07:17:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23368 Sat 24 Mar 2018 07:16:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23418 Sat 24 Mar 2018 07:13:54 AEDT ]]>